Dr. Lara on Epacadostat Plus Pembrolizumab in RCC

Primo N. Lara, MD
Published: Friday, Jun 23, 2017



Primo N. Lara, MD, associate director for translational research, UC Davis Comprehensive Cancer Center, discusses epacadostat plus pembrolizumab (Keytruda) in patients with metastatic renal cell carcinoma (RCC).

The phase Ib/II trial showed encouraging response rates and safety signals for this combination, particularly with patients who had minimally pretreated disease.

The confirmed response rate was 47%. In this study, only 17% of patients experienced grade 3 or higher toxicity, which is what is expected with single agent checkpoint inhibitor therapy.
 
SELECTED
LANGUAGE


Primo N. Lara, MD, associate director for translational research, UC Davis Comprehensive Cancer Center, discusses epacadostat plus pembrolizumab (Keytruda) in patients with metastatic renal cell carcinoma (RCC).

The phase Ib/II trial showed encouraging response rates and safety signals for this combination, particularly with patients who had minimally pretreated disease.

The confirmed response rate was 47%. In this study, only 17% of patients experienced grade 3 or higher toxicity, which is what is expected with single agent checkpoint inhibitor therapy.
 

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: Addressing Post-Transplant Obstacles: Current and Emerging Strategies to Evolve the Standard of Care for Patients With Graft-Versus-Host DiseaseMar 28, 20192.0
2017 Year in Review™: Clinical Impact of Immunotherapies in the Treatment of CancerMar 30, 20191.75
Publication Bottom Border
Border Publication
x