HER2-Positive Colorectal Cancer: Novel Approaches

EP. 1: Colorectal Cancer: Prevalence, Workup, and Molecular Subtypes
ByTanios S. Bekaii-Saab, MD, Mayo Clinic,Cathy Eng, MD, FACP, FASCO, Vanderbilt-Ingram Cancer Center,Pashtoon M. Kasi, MD, MBBS, MS,Aparna R. Parikh, MD Opening their discussion on colorectal cancer, expert panelists consider its growing prevalence and highlight key molecular subtypes.

EP. 2: Colorectal Cancer: An Overview on Molecular Profiling
ByTanios S. Bekaii-Saab, MD, Mayo Clinic,Cathy Eng, MD, FACP, FASCO, Vanderbilt-Ingram Cancer Center,Pashtoon M. Kasi, MD, MBBS, MS,Aparna R. Parikh, MD Shared insight on appropriate molecular lab testing options that should be explored following a diagnosis of colorectal cancer.

EP. 3: Role of HER2 Expression in Colorectal Cancer
ByTanios S. Bekaii-Saab, MD, Mayo Clinic,Cathy Eng, MD, Vanderbilt University,Pashtoon M. Kasi, MD, MBBS, MS,Aparna R. Parikh, MD A brief review of HER2 amplification and how it may impact the treatment pathway for patients with a diagnosis of colorectal cancer.

EP. 4: Role of Circulating Tumor DNA Testing in Colorectal Cancer
ByTanios S. Bekaii-Saab, MD, Mayo Clinic,Cathy Eng, MD, Vanderbilt University,Pashtoon M. Kasi, MD, MBBS, MS,Aparna R. Parikh, MD In the context of colorectal cancer clinical trials, panelists reflect on the role of liquid biopsies to help inform treatment decisionmaking.

EP. 5: Treatment Algorithm for Metastatic Colorectal Cancer
ByTanios S. Bekaii-Saab, MD, Mayo Clinic,Cathy Eng, MD, Vanderbilt University,Pashtoon M. Kasi, MD, MBBS, MS,Aparna R. Parikh, MD Broadening their conversation, expert oncologists define the treatment algorithm for patients diagnosed with colorectal cancer.

EP. 6: HER2-Amplified Colorectal Cancer: Clinical Trial Data
ByTanios S. Bekaii-Saab, MD, Mayo Clinic,Cathy Eng, MD, Vanderbilt University,Pashtoon M. Kasi, MD, MBBS, MS,Aparna R. Parikh, MD A focused discussion on HER2-amplified colorectal cancer and respective clinical trials that inform use of targeted agents in this setting.

EP. 7: Real-World Use of HER2-Directed Therapies in Colorectal Cancers
ByTanios S. Bekaii-Saab, MD, Mayo Clinic,Cathy Eng, MD, Vanderbilt University,Pashtoon M. Kasi, MD, MBBS, MS,Aparna R. Parikh, MD Expert perspectives on the real-world use of HER2-directed therapies in patients with HER2-amplified colorectal cancer.

EP. 8: Evolutions in the HER2-Amplified CRC Treatment Landscape
ByTanios S. Bekaii-Saab, MD, Mayo Clinic,Cathy Eng, MD, Vanderbilt University,Pashtoon M. Kasi, MD, MBBS, MS,Aparna R. Parikh, MD Looking toward the future management of HER2-amplified colorectal cancer, panelists reflect on ongoing clinical trials and evolving treatment strategies.

EP. 9: Audience Q&A: Best Practices in Managing HER2-Amplified CRC
ByTanios Bekaii-Saab, MD, FACP, Mayo Clinic,Cathy Eng, MD, Vanderbilt University,Pashtoon M. Kasi, MD, MBBS, MS,Aparna R. Parikh, MD Fielding questions from the audience, expert oncologists discuss clinical trials, molecular testing, and early-stage disease in the context of HER2-amplified colorectal cancer.