Recent Data and New Learnings in Myeloproliferative Neoplasms

EP. 1: Overview on Essential Thrombocythemia and Polycythemia Vera Management
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD Expert perspectives on the respective treatment landscapes of essential thrombocytopenia (ET) and polycythemia vera (PV) following the ASH 2022 Annual Meeting.

EP. 2: Role of Symptom Burden in Thrombocythemia and Polycythemia Vera
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD Shared insight on how a patient’s symptom burden can impact management strategies within essential thrombocytopenia and polycythemia vera.

EP. 3: Novel Therapy in Myelofibrosis: Momelotinib
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben A. Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD Switching their focus to myelofibrosis management, expert panelists reflect on clinical data behind momelotinib, a novel JAK2 inhibitor.

EP. 4: Therapy in Myelofibrosis: Pacritinib
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben A. Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD Key opinion leaders on myeloproliferative neoplasms review clinical data behind pacritinib therapy in the setting of myelofibrosis.

EP. 5: Myelofibrosis: Nuancing the Potential of Disease Modification
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben A. Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD A brief review of the biology of myelofibrosis, the potential for disease modification, and subsequent implications for treatment.

EP. 6: Therapy in Myelofibrosis: Fedratinib and Ruxolitinib Strategies
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben A. Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD Closing out their discussion on the management of myelofibrosis, panelists highlight updated data with fedratinib and ruxolitinib, respectively.

EP. 7: What is the Role of Transplant in Managing Patients With Myelofibrosis?
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben A. Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD Expert panelists consider the ongoing role of transplant for patients with myelofibrosis and discuss when it is more appropriate to explore systemic therapy options.

EP. 8: Myeloproliferative Neoplasms: Targeting CALR With Novel Therapy
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben A. Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD Key opinion leaders on myeloproliferative neoplasms review the potential of CALR as a therapeutic target following data from the ASH 2022 Annual Meeting.

EP. 9: An Expanding Armamentarium in MPNs: Therapeutic Strategies Under Investigation
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben A. Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD A broad and comprehensive review of novel targeted agents under investigation in the setting of myeloproliferative neoplasm management.

EP. 10: Sequencing and Managing Combination Therapy in Myeloproliferative Neoplasms
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben A. Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD Following their overview on novel treatment modalities in myeloproliferative neoplasms, expert panelists consider how best to sequence and manage novel therapies in practice.

EP. 11: Myeloproliferative Neoplasm Management: Future Directions in Care
ByNaveen Pemmaraju, MD,John Mascarenhas, MD,Ruben A. Mesa, MD,Jeanne M. Palmer, MD,Stephen Oh, MD, PhD Closing out their discussion on myeloproliferative neoplasms, key opinion leaders share excitement for future evolutions in the treatment paradigm.