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Can Immunotherapy Bypass Sequential Care in RCC?

Jason Harris
Published: Friday, Feb 02, 2018
David McDermott, MD

David McDermott, MD
Is immunotherapy the future of first-line treatment for advanced renal cell carcinoma (RCC)? The answer, according to David F. McDermott, MD, leader of the kidney cancer program at DanaFarber/Harvard Cancer Center, is “maybe.”

 

Table. Key Findings From the Check-Mate-214 Trial1

Favorable risk patients, in contrast, had a significantly higher confirmed objective response rate (ORR) with sunitinib versus the combination arm (52% vs 29%, P = .0002), as well as a significantly longer PFS (25.1 vs 15.3 months; P <.0001).
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