How Elbow Grease and Inspiration Forged a Winning Career

Katie Kosko
Published: Saturday, Mar 03, 2018
Dr Larry Norton

Larry Norton, MD
He was once laughed at for pouring his talent into the “reviled” field of oncology, but Larry Norton, MD, said he was driven by his passion to learn about cancer. In fact, even now, seldom do his thoughts or actions stray far from the problem of how to cure this disease. “There’s a constant churn of activity toward making a difference— my own research, teaching, taking care of patients,” said Norton, who is deputy physician in chief for breast cancer at Memorial Sloan Kettering (MSK) Cancer Center, New York, New York, where he also serves as medical director of the Evelyn H. Lauder Breast Center.

Norton, who is conservatory trained, was initially interested in becoming a professional musician. He can play multiple instuments, from the keyboard to the guitar to woodwinds. In 2010, he even hit the stage for a duet with Sir Elton John at a breast cancer charity event. Elton played the piano, Norton the harmonica—a performance the celebrated oncologist and musical talent says he will never forget.

The Aha Moment

As a youth, Norton knew the extremes of environment that New York has to offer. He lived in the Bronx, the poorest borough of New York City, and Valley Stream, a suburb of wealthy Nassau County in Long Island. His father was a journalist and his mother a secretary. Somehow, the bug for medicine flourished in the younger generation. His sister became a pediatric radiologist and is now retired. But before medicine even crossed his mind, Norton earned a living as a truck driver by delivering fishing tackle.

“I thought it was the most magical thing I had ever seen in my life,” Norton said. “It was like I saw this monster that was devouring this patient and a medicine—carefully chosen to work in this setting—was making this obviously fatal process just go away. Everything about that experience was something that I knew I had to do, and that convinced me that I belonged in medicine and not in music. The fact is that it was the great science, the great clinical thinking, and Regelson’s intuition—I mean everything good about the world was in that one case. And that was my revelation.”

A Pioneering Moment

When Norton entered the field of oncology, it was overshadowed by pessimism. Few believed that oncology would become a promising branch of medicine unto itself. In medical school, Norton’s mentor once said to him, “Larry, you’re so good with your hands. You belong in surgery. It’s surgery that really helps people. You don’t want to get involved in drug treatment of cancer. It’s never going to go anywhere. We can’t kill cancer with drugs.”
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Online CME Activities
TitleExpiration DateCME Credits
Advances in™ Therapies for Patients With ALK-Positive Lung Cancers: More Options…More Decisions…Better OutcomesAug 30, 20191.5
Community Practice Connections™: PARP Inhibition in Breast Cancer: Practical Methods to Interpret and Apply the Evidence for Your PatientsAug 30, 20191.5
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