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Old-Fashioned Biology Trumps Technological Potential

Maurie Markman, MD
Published: Wednesday, Apr 10, 2019
Maurie Markman, MD

Maurie Markman, MD
There is no debate regarding the spectacular role that technology has played and continues to play in the evolution of our understanding of the fundamental molecular biology of cancer and its development, progression, and resistance to currently available therapeutics. Further, the ability to sequence and subsequently interrogate the genome of an individual patient with cancer (somatic or germline) has impressively advanced the paradigm-changing concept of precision cancer medicine, whereby therapy will increasingly be based on documented molecular characteristics within an individual’s cancer or germline profile rather than simply on the site of origin or the histologic appearance of the malignancy.
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