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Commentary|Videos|May 30, 2025

Addressing CNS Involvement in ROS1+ NSCLC

Author(s)Charu Aggarwal, MD, MPH, Geoffrey Liu, MSc, MD

Fact checked by: Chris Ryan

Charu Aggarwal, MD, MPH, and Geoffrey Liu, MSc, MD, discuss CNS involvement in ROS1-positive non–small cell lung cancer.

Episodes in this series

Charu Aggarwal, MD, MPH, and Geoffrey Liu, MSc, MD, discuss the prevalence of ROS1 fusions in non–small cell lung cancer.

EP. 1 The Prevalence of ROS1 Fusions in Advanced NSCLC

Charu Aggarwal, MD, MPH, and Geoffrey Liu, MSc, MD, discuss treatment sequencing in ROS1-positive non–small cell lung cancer.

EP. 2 Treatment Sequencing Decisions in ROS1+ NSCLC

Charu Aggarwal, MD, MPH, and Geoffrey Liu, MSc, MD, discuss TKI selection in ROS1-positive non–small cell lung cancer.

EP. 3 Selecting a TKI in ROS1+ NSCLC Management

Charu Aggarwal, MD, MPH, and Geoffrey Liu, MSc, MD, discuss CNS involvement in ROS1-positive non–small cell lung cancer.

EP. 4 Addressing CNS Involvement in ROS1+ NSCLC

Charu Aggarwal, MD, MPH, and Geoffrey Liu, MSc, MD, discuss data for taletrectinib in ROS1-positive non–small cell lung cancer.

EP. 5 Pooled Data for Taletrectinib in ROS1+ NSCLC

Charu Aggarwal, MD, MPH, and Geoffrey Liu, MSc, MD, on how FDA approval of taletrectinib would affect ROS1-positive non–small cell lung cancer management.

EP. 6 Another FDA-Approved Option? The Potential Role for Taletrectinib in ROS1+ NSCLC

Charu Aggarwal, MD, MPH, and Geoffrey Liu, MSc, MD, on novel approaches being investigated in ROS1-positive non–small cell lung cancer.

EP. 7 Novel Treatment Approaches Under Investigation in ROS1+ NSCLC

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