Opinion|Videos|April 1, 2026

Building Upon the Lenalidomide/Rituximab Backbone in R/R Follicular Lymphoma

Loretta J. Nastoupil, MD, and Amitkumar Mehta, MD, discuss methods of building on the lenalidomide/rituximab backbone in relpased/refractory follicular lymphoma.

Loretta J. Nastoupil, MD, and Amitkumar Mehta, MD, discuss how the lenalidomide/rituximab (R²) backbone continues to serve as a foundation for novel combination strategies in relapsed/refractory follicular lymphoma. Nastoupil reviews the clinical impact of adding agents such as tafasitamab to R² and how recent approvals are shaping practice. Mehta underscores how updated NCCN Guidelines and emerging triplet regimens are influencing second-line treatment decision-making.


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