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Commentary|Videos|April 30, 2025

CIRCULATE-Japan: Diving Into ctDNA and DFS Data in Stage II-IV CRC

Author(s)Scott Kopetz, MD, PhD, FACP, Mark A. Lewis, MD

Fact checked by: Chris Ryan

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, on data from the GALAXY arm of CIRCULATE-Japan for ctDNA in stage II to IV CRC.

Episodes in this series

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, on why ctDNA remains a focus of research in colorectal cancer.

EP. 1 Why ctDNA Remains a Focal Point in CRC Research

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, on data from the GALAXY arm of CIRCULATE-Japan for ctDNA in stage II to IV CRC.

EP. 2 CIRCULATE-Japan: Diving Into ctDNA and DFS Data in Stage II-IV CRC

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, discuss how to approach conversations about ctDNA with patients with CRC.

EP. 3 Talking to Patients With CRC About ctDNA

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, discuss findings for ctDNA in stage II/III CRC from the BESPOKE CRC trial.

EP. 4 Implications From the BESPOKE CRC Study Evaluating ctDNA in Stage II-III CRC

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, discuss ongoing research in CRC utilizing ctDNA.

EP. 5 How ctDNA Is Informing Ongoing Trials in CRC

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, discuss how ctDNA assays have improved MRD detection in CRC.

EP. 6 The Evolution of ctDNA Assays in CRC

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