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Commentary|Videos|April 30, 2025

The Evolution of ctDNA Assays in CRC

Author(s)Scott Kopetz, MD, PhD, FACP, Mark A. Lewis, MD

Fact checked by: Chris Ryan

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, discuss how ctDNA assays have improved MRD detection in CRC.

Episodes in this series

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, on why ctDNA remains a focus of research in colorectal cancer.

EP. 1 Why ctDNA Remains a Focal Point in CRC Research

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, on data from the GALAXY arm of CIRCULATE-Japan for ctDNA in stage II to IV CRC.

EP. 2 CIRCULATE-Japan: Diving Into ctDNA and DFS Data in Stage II-IV CRC

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, discuss how to approach conversations about ctDNA with patients with CRC.

EP. 3 Talking to Patients With CRC About ctDNA

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, discuss findings for ctDNA in stage II/III CRC from the BESPOKE CRC trial.

EP. 4 Implications From the BESPOKE CRC Study Evaluating ctDNA in Stage II-III CRC

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, discuss ongoing research in CRC utilizing ctDNA.

EP. 5 How ctDNA Is Informing Ongoing Trials in CRC

Scott Kopetz, MD, PhD, FACP, and Mark A. Lewis, MD, discuss how ctDNA assays have improved MRD detection in CRC.

EP. 6 The Evolution of ctDNA Assays in CRC

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