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Opinion|Videos|December 14, 2023

Clinical Data Review of Hepatotoxicity in Frontline KRAS G12C Inhibition

Author(s)Joshua K. Sabari, MD, Edward B. Garon, MD, MS

A comprehensive review of hepatotoxicity in ongoing studies evaluating KRAS inhibitors in the frontline setting, highlighting adagrasib and sotorasib in the KRYSTAL-7 and CodeBreaK 100 studies, respectively.

Episodes in this series

EP. 1 The State of Targeted Therapies in NSCLC

EP. 1 The State of Targeted Therapies in NSCLC

EP. 2 Frontline Treatments for KRAS G12C-Mutation mNSCLC

EP. 2 Frontline Treatments for KRAS G12C-Mutation mNSCLC

EP. 3 Clinical Perspectives of KRAS G12C Inhibitors in NSCLC Mutations

EP. 3 Clinical Perspectives of KRAS G12C Inhibitors in NSCLC Mutations

EP. 4 The Role of KRAS G12C Inhibitors in Frontline Metastatic NSCLC

EP. 4 The Role of KRAS G12C Inhibitors in Frontline Metastatic NSCLC

EP. 5 Clinical Data Review of Hepatotoxicity in Frontline KRAS G12C Inhibition

EP. 5 Clinical Data Review of Hepatotoxicity in Frontline KRAS G12C Inhibition

EP. 6 Disease Progression Beyond Frontline KRAS G12C Inhibitors

EP. 6 Disease Progression Beyond Frontline KRAS G12C Inhibitors

EP. 7 CodeBreaK 200: Sotorasib in Second Line KRAS G12C-Mutated NSCLC

EP. 7 CodeBreaK 200: Sotorasib in Second Line KRAS G12C-Mutated NSCLC

EP. 8 KRAS Inhibitors: Hepatotoxicity and Adverse Events in 2L Metastatic NSCLC

EP. 8 KRAS Inhibitors: Hepatotoxicity and Adverse Events in 2L Metastatic NSCLC

EP. 9 Practical Management of Hepatotoxicity in KRAS G12C Inhibitors

EP. 9 Practical Management of Hepatotoxicity in KRAS G12C Inhibitors

EP. 10 Future Perspectives in KRAS G12C-Mutated NSCLC

EP. 10 Future Perspectives in KRAS G12C-Mutated NSCLC

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