Podcast

D'Amato Discusses Research and Resistance Mechanisms in Sarcoma and Gastrointestinal Stromal Tumor

Author(s):

Dr D’Amato discusses research in sarcoma and gastrointestinal stromal tumor, incorporating circulating tumor DNA analysis into routine reevaluation of patients with progressive disease, and the importance of establishing a drug’s clinical profile in non–trial target ethnic populations.

Welcome to OncLive On Air®! I’m your host today, Caroline Seymour.

OncLive On Air® is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive® covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, sponsored by Deciphera Pharmaceuticals, we had the pleasure of speaking with Gina Z. D’Amato, MD, to discuss research in sarcoma and gastrointestinal stromal tumor that was presented at the 2022 ASCO Annual Meeting, 2023 Gastrointestinal Cancers Symposium, and 2023 January ASCO Plenary Series.

Dr D’Amato is an associate professor of medicine and sarcoma medical oncology and the assistant director of clinical research at Sylvester Comprehensive Cancer Center, part of the University of Miami Health System in Florida.

In our exclusive interview, Dr D’Amato discussed the significance of incorporating circulating tumor DNA analysis into routine reevaluation of patients with progressive disease, emphasized the importance of establishing a drug’s clinical profile in non–trial target ethnic populations, and highlighted a first-in-human trial evaluating IDRX-42, a novel TKI that could overcome acquired resistance to standard therapy. 

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