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Opinion|Videos|January 19, 2026

Data for Duvelisib Plus Chidamide/CHOP in Newly Diagnosed AITL

Author(s)Francine Foss, MD, Matthew Lunning, DO, FACP

Francine Foss, MD, and Matthew Lunning, DO, FACP, discuss findings for duvelisib plus chidamide and CHOP in newly diagnosed angioimmunoblastic T-cell lymphoma.

Episodes in this series

EP. 1 Clinical Considerations for the Diagnosis and Management of Peripheral T-Cell Lymphoma

EP. 1 Clinical Considerations for the Diagnosis and Management of Peripheral T-Cell Lymphoma

EP. 2 Treatment Considerations for Newly Diagnosed vs Relapsed PTCL

EP. 2 Treatment Considerations for Newly Diagnosed vs Relapsed PTCL

EP. 3 PRIMO Trial: Data for Duvelisib in R/R PTCL

EP. 3 PRIMO Trial: Data for Duvelisib in R/R PTCL

EP. 4 Previewing the Phase 3 TERZO Trial of Duvelisib vs Gemcitabine or Bendamustine in Nodal TFH PTCL

EP. 4 Previewing the Phase 3 TERZO Trial of Duvelisib vs Gemcitabine or Bendamustine in Nodal TFH PTCL

EP. 5 Data for Duvelisib Plus Chidamide/CHOP in Newly Diagnosed AITL

EP. 5 Data for Duvelisib Plus Chidamide/CHOP in Newly Diagnosed AITL

EP. 6 Other Standout Data in PTCL From ASH 2025

EP. 6 Other Standout Data in PTCL From ASH 2025

Francine Foss, MD, and Matthew Lunning, DO, FACP, discuss emerging data evaluating duvelisib (Copiktra) in combination with chidamide and CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) in patients with newly diagnosed angioimmunoblastic T-cell lymphoma (AITL). They review early efficacy signals and safety considerations associated with this combination strategy. Foss and Lunning consider how these findings may support novel frontline approaches in AITL.

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