
Commentary|Videos|May 14, 2025
Data for RP1 Plus Nivolumab in Metastatic Melanoma After Prior PD-1 Inhibition
Author(s)Michael A. Postow, MD, Chenyang Zhan, MD, PhD
Michael A. Postow, MD, and Chenyang Zhan, MD, PhD, break down data from the IGNYTE trial of RP1 plus nivolumab in advanced melanoma after PD-1 inhibition.
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Here is your cheat sheet to all therapeutic options that were cleared by the FDA in August 2026 spanning tumor types.

The regulatory path to approval for RP1 plus nivolumab in anti–PD-1–pretreated melanoma ran through 3 BLAs, 2 CRLs, and a divided advisory committee vote.
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