
Commentary|Videos|May 14, 2025
Where RP1 Plus Nivolumab Could Fit in the Treatment Paradigm for Advanced Melanoma Post–PD-1 Inhibition
Author(s)Michael A. Postow, MD, Chenyang Zhan, MD, PhD
Michael A. Postow, MD, and Chenyang Zhan, MD, PhD, discuss where RP1 plus nivolumab could fit in the advanced melanoma treatment paradigm.
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Here is your cheat sheet to all therapeutic options that were cleared by the FDA in August 2026 spanning tumor types.

The regulatory path to approval for RP1 plus nivolumab in anti–PD-1–pretreated melanoma ran through 3 BLAs, 2 CRLs, and a divided advisory committee vote.
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