Video

Dr. Hurvitz on Steps to Take With HER2-Positive Breast Cancer Research

Sara Hurvitz, MD, medical oncologist, General Internal Medicine, Hematology and Oncology at UCLA, discusses steps needed to take in the field of HER2-positive breast cancer from a research perspective.

Sara Hurvitz, MD, medical oncologist, General Internal Medicine, Hematology and Oncology at UCLA, discusses necessary steps that need to be taken in the field of HER2-positive breast cancer from a research perspective.

Researchers are beginning to have a deeper understanding of the different long-term and surgical outcomes of patients with hormone-receptor—positive, HER2-positive breast cancer compared with those who are HR-negative, Hurvitz explains. Outcomes related to PI3K activation status, she adds, may help inform decision-making and treatment options.

Looking at CDK4/6 inhibiton will also be an important area to study further, she adds. Future studies should explore combining CDK4/6 inhibitors with HER2-targeted agents as well as with endocrine therapy.

Related Videos
Alberto Montero, MD, MBA, CPHQ, clinical director, Breast Cancer Medical Oncology Program, University Hospitals Seidman Cancer Center; associate professor, medicine, Case Western Reserve University School of Medicine
JURCZACK
Adam E. Singer, MD, PhD, health sciences clinical instructor, medicine, division lead, Kidney Cancer, Division of Hematology/Oncology, UCLA Health
Dr Burke on the Assessment of Barriers to Initiating Venetoclax-Based Regimens for CLL
Bradley McGregor, MD,
Ira Zackon, MD
Jacob E. Berchuck, MD
David A. Braun, MD, PhD