Dr. Li Discusses the PROFILE Crizotinib Clinical Trials | OncLive

Dr. Li Discusses the PROFILE Crizotinib Clinical Trials

September 1, 2011

Dr. Tianhong Li from UC Davis Cancer Center Discusses the PROFILE Crizotinib Clinical Trials

Tianhong (Tina) Li, MD, PhD, assistant professor, co-director of Phase I Program, UC Davis Cancer Center, discusses the PROFILE clinical trials examining ALK-positive non-small cell lung cancer patients that led to the FDA approval of Pfrizer's crizotinib (Xalkori).

The 1001 trial examined 119 ALK-positive NSCLC patients with a 61% overall response rate and 69% partial response rates. The 1005 trial also exhibited great results, with 136 patients and a 50% overall response rate, including 1 complete response and 67% partial response.


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