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Dr. Tianhong Li from UC Davis Cancer Center Discusses the PROFILE Crizotinib Clinical Trials
Tianhong (Tina) Li, MD, PhD, assistant professor, co-director of Phase I Program, UC Davis Cancer Center, discusses the PROFILE clinical trials examining ALK-positive non-small cell lung cancer patients that led to the FDA approval of Pfrizer's crizotinib (Xalkori).
The 1001 trial examined 119 ALK-positive NSCLC patients with a 61% overall response rate and 69% partial response rates. The 1005 trial also exhibited great results, with 136 patients and a 50% overall response rate, including 1 complete response and 67% partial response.