Dr. Sandra Demaria on Radiation and Immunotherapy Combination Regimens

June 10, 2016
Sandra Demaria, MD

Sandra Demaria, MD, assistant professor of Radiation Oncology, (Interim), Radiation Oncology, Weill Cornell Medical College and New-York Presbyterian, discusses the synergy with radiation therapy and immunotherapy as a potential combination regimen for patients with cancer.

Sandra Demaria, MD, assistant professor of Radiation Oncology, (Interim), Radiation Oncology, Weill Cornell Medical College and New-York Presbyterian, discusses the synergy with radiation therapy and immunotherapy as a potential combination regimen for patients with cancer.

Radiation therapy has various effects on patients depending on the way it is administered, Demaria explains. Nevertheless, there is a synergy that exists between radiation therapy and immunotherapy that has an effect on the tumor microenvironment.

Evidence suggests that T-cell responses can occur with such a combination, she adds, while ongoing research is examining additional immunotherapy and radiation therapy agents. This is particulary interesting, Demaria says, because radiation therapy is readily available; however, it could now be administered in a completely different way to induce a systemic effect on tumors.


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