Dr. Shore Comments on the Approval of Radium-223

Video

Neal D. Shore, MD, FACS, medical director, Carolina Urologic Research Center, Myrtle Beach, discusses the approval of radium-223 for patients with bone metastases from prostate cancer.

Neal D. Shore, MD, FACS, medical director, Carolina Urologic Research Center, Myrtle Beach, discusses the approval of radium-223 for patients with bone metastases from prostate cancer.

Shore believes that the FDA approved radium-223 so quickly because of the robust data regarding efficacy and toleration. Radium-223 demonstrated an improvement in survival and delay in skeletal complications for patients with bone metastases and was well-tolerated, with no significant myelosuppression. As the radioisotope is cleared through the intestinal tract and excreted fecally, mild events of diarrhea were observed, Shore says.

Radium-223 is given intravenously over a period of about 45-60 seconds and is administered once every 4 weeks for 6 administrations. Additionally, Shore says, the agent must be administered by someone with the appropriate licensure.

Related Videos
Timothy Yap, MBBS, PhD, FRCP
Muhamed Baljevic, MD, FACP
Kathleen A. Dorritie, MD
David L. Porter, MD, director, Cell Therapy and Transplant, Jodi Fisher Horowitz Professor in Leukemia Care Excellence, Penn Medicine
Muhamed Baljevic, MD
Sumanta Kumar Pal, MD, FASCO,
Carrie L. Kitko, MD
Kara N. Maxwell, MD, PhD
Kian-Huat Lim, MD, PhD
Thomas F. Gajewski, MD, PhD