Dr. Xifeng Wu on Prognostic Factor of Obesity-Related Genes in RCC

Xifeng Wu, MD, PhD, chair, Department of Epidemiology, Division of OVP, Cancer Prevention and Population Sciences, director, Center for Translational and Public Health Genomics, professor, The University of Texas MD Anderson Cancer Center, discusses the prognostic factor of obesity-related genes in patients with renal cell carcinoma (RCC).

Xifeng Wu, MD, PhD, chair, Department of Epidemiology, Division of OVP, Cancer Prevention and Population Sciences, director, Center for Translational and Public Health Genomics, professor, The University of Texas MD Anderson Cancer Center, discusses the prognostic factor of obesity-related genes in patients with renal cell carcinoma (RCC).

In a study, researchers found that LEPR methylation is associated with kidney cancer tumorgenesis, Wu explains.

Additionally, LEPR methylation levels were found to be significantly high in tumor tissue versus normal tissue. Additionally, these methylation levels are also associated with recurrence risk for kidney cancer as well as the clinical feature of the disease, Wu adds.

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