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Opinion|Videos|July 30, 2024

Emerging Data with BTKi Resistance: Expert Insights and Treatment Implications

Author(s)Catherine C. Coombs, MD, Bita Fakhri, MD, MPH, John N. Allan, MD

The panel addresses the intricacies of treating patients with chronic lymphocytic leukemia who experience treatment resistance.

Episodes in this series

A panel of 3 experts on CLL

EP. 1 Patient with Newly Diagnosed CLL with High-Risk Features

A panel of 3 experts on CLL

EP. 2 Expert Perspectives on 1L Treatment Approaches in Newly Diagnosed CLL

A panel of 3 experts on CLL

EP. 3 Navigating Continuous BTKi Therapy for CLL in the 1L Setting

A panel of 3 experts on CLL

EP. 4 Implications of Real-World Data in the 1L Treatment of High-Risk CLL

A panel of 3 experts on CLL

EP. 5 Expert Perspectives on Venetoclax-Based 1L Treatment Strategies in CLL

A panel of 3 experts on CLL

EP. 6 Considerations for 1L Doublet and Triplet Therapy with Venetoclax in CLL

A panel of 3 experts on CLL

EP. 7 Perspectives on Shared Decision-Making in the Treatment of CLL

A panel of 3 experts on CLL

EP. 8 Strategies for Optimizing Venetoclax-Based Treatment for Patients with CLL

A panel of 3 experts on CLL

EP. 9 Expert Insights for Long-Term Treatment Planning in CLL

A panel of 3 experts on CLL

EP. 10 Patient with R/R CLL Treated with 2L Venetoclax Therapy

A panel of 3 experts on CLL

EP. 11 Navigating 2L Treatment Options in CLL

A panel of 3 experts on CLL

EP. 12 Emerging Data with BTKi Resistance: Expert Insights and Treatment Implications

A panel of 3 experts on CLL

EP. 13 Management Strategies for BTKi-Related CVAEs in CLL

A panel of 3 experts on CLL

EP. 14 Updates in CLL Treatment Strategies with Noncovalent BTKis

A panel of 3 experts on CLL

EP. 15 Looking Ahead: Novel Therapies and Future Perspectives in the Treatment of CLL

Video content above is prompted by the following questions:

Briefly discuss insights regarding emerging resistance data and its potential implications on treatment decisions/practices.
- In patients who progress on 1L therapy with BTKi, do you test for the presence of BTK resistance mutations?
- How do you interpret available data to the clinical practice setting?

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