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Commentary|Videos|January 23, 2025

Emerging Mutation Analysis from the OPTIC Trial

Author(s)Javier Pinilla, MD, PhD, Talha Badar, MBBS, MD

Javier Pinilla, MD, PhD, and Talha Badar, MBBS, MD, on the implications of the mutational analysis for ponatinib in the OPTIC trial in CP-CML.

Episodes in this series

Javier Pinilla, MD, PhD, and Talha Badar, MBBS, MD, on the implications of the FDA approval of asciminib in newly diagnosed CP-CML.

EP. 1 Implications of the FDA Approval of Asciminib for Newly Diagnosed, Ph+ CP-CML

Javier Pinilla, MD, PhD, and Talha Badar, MBBS, MD, discuss factors that influence later-line treatment choices in chronic myeloid leukemia.

EP. 2 Factors That Influence Treatment Decisions in Later-Line CML

Javier Pinilla, MD, PhD, and Talha Badar, MBBS, MD, discuss 5-year data for ponatinib in pretreated CP-CML.

EP. 3 5-year Data for Ponatinib in Pretreated CP-CML from the OPTIC Trial

Javier Pinilla, MD, PhD, and Talha Badar, MBBS, MD, on the implications of the mutational analysis for ponatinib in the OPTIC trial in CP-CML.

EP. 4 Emerging Mutation Analysis from the OPTIC Trial

Javier Pinilla, MD, PhD, and Talha Badar, MBBS, MD, discuss dosing strategies for ponatinib in CML and ALL.

EP. 5 Dosing Strategies for Ponatinib in CML and ALL

Javier Pinilla, MD, PhD, and Talha Badar, MBBS, MD, discuss data for ponatinib plus chemotherapy in Ph-positive ALL.

EP. 6 The Role of Frontline Ponatinib Plus Chemo in Ph+ ALL

Javier Pinilla, MD, PhD, and Talha Badar, MBBS, MD, detail factors for selecting a TKI in later lines of therapy in chronic myeloid leukemia.

EP. 7 Selecting a TKI in Subsequent Lines of Therapy in CML

Javier Pinilla, MD, PhD, and Talha Badar, MBBS, MD, highlight key data in CML and ALL presented at the 2024 ASH Annual Meeting.

EP. 8 Highlighting Key CML/ALL Data Presented at ASH 2024

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