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|Videos|December 6, 2021

ESMO 2021 Updates in Gastric Cancer and Colorectal Cancer

Author(s)Sam Klempner, MD, Massachusetts General Hospital , Daniel H. Ahn, DO, Mayo Clinic, Nataliya V. Uboha, MD, PhD

Sam Klempner, MD; Daniel H. Ahn, DO; Nataliya V. Uboha, MD, PhD; and Manish A. Shah, MD, FASCO, review recent updates in second-line gastric cancer, CAR T-cell therapy in solid tumors, and colorectal cancer presented at ESMO 2021.

Episodes in this series

EP. 1 ESMO 2021 Updates in Metastatic Esophageal Squamous Cell Carcinoma

EP. 1 ESMO 2021 Updates in Metastatic Esophageal Squamous Cell Carcinoma

EP. 2 ESMO 2021 Updates in Gastroesophageal and Gastric Adenocarcinomas

EP. 2 ESMO 2021 Updates in Gastroesophageal and Gastric Adenocarcinomas

EP. 3 ESMO 2021 Updates in HER2+ Metastatic Gastric and Gastroesophageal Cancer

EP. 3 ESMO 2021 Updates in HER2+ Metastatic Gastric and Gastroesophageal Cancer

EP. 4 ESMO 2021 Updates in Gastric Cancer and Colorectal Cancer

EP. 4 ESMO 2021 Updates in Gastric Cancer and Colorectal Cancer

Data from the following clinical trials are discussed:

1382P - Phase 1b/2 open-label, randomized evaluation of second-line atezolizumab (atezo) + linagliptin (lina) vs ramucirumab (ram) + paclitaxel (pac) in MORPHEUS-gastric cancer (MORPHEUS)
1372O - CLDN 18.2-targeted CAR-T cell therapy in patients with cancers of the digestive system
LBA6 - KRYSTAL-1: Adagrasib (MRTX849) as monotherapy or combined with cetuximab (Cetux) in patients (Pts) with colorectal cancer (CRC) harboring a KRASG12C mutation KRYSTAL-1

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