FDA Approval Insights: Momelotinib in Myelofibrosis With Anemia

Commentary
Podcast

In Partnership With:

Dr Kuykendall discusses the FDA approval of momelotinib in myelofibrosis with anemia, key data from the MOMENTUM trial, and how momelotinib alters the myelofibrosis treatment paradigm.

Welcome to OncLive On Air®! I’m your host today, Ashling Wahner.

OncLive On Air® is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive® covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, sponsored by GSK, we had the pleasure of speaking with Andrew Kuykendall, MD, about the FDA approval of momelotinib in myelofibrosis with anemia. Dr Kuykendall is an assistant member in the Department of Malignant Hematology at Moffitt Cancer Center in Tampa, Florida.

On September 15, 2023, the FDA approved momelotinib for the treatment of adult patients with intermediate- or high-risk myelofibrosis with anemia. This regulatory decision was backed by findings from the phase 3 MOMENTUM trial (NCT04173494). In MOMENTUM, 25% of patients who received momelotinib achieved a Myelofibrosis Symptom Assessment Form v4.0 total symptom score reduction of at least 50% vs 9% of patients who received danazol.

In our exclusive interview, Dr Kuykendall discussed the significance of this approval, key data from MOMENTUM, and how momelotinib alters the myelofibrosis treatment paradigm.

___

That’s all we have for today! Thank you for listening to this episode of OncLive On Air®, sponsored by GSK. Check back on Mondays and Thursdays for exclusive interviews with leading experts in the oncology field.

For more updates in oncology, be sure to visit www.OncLive.com and sign up for our e-newsletters.

OncLive® is also on social media. On Twitter, follow us at @OncLive. On Facebook, like us at OncLive, and follow our OncLive page on LinkedIn.

If you liked today’s episode of OncLive On Air®, please consider subscribing to our podcast on Apple Podcasts, Spotify, Google Podcasts, Amazon Music, and many of your other favorite podcast platforms,* so you get a notification every time a new episode is posted. While you are there, please take a moment to rate us!

Thanks again for listening to OncLive On Air®.

*OncLive On Air® is available on: Apple Podcasts, Google Podcasts, Spotify, Amazon Music, Audacy, CastBox, Deezer, iHeart, JioSaavn, Listen Notes, Player FM, Podcast Addict, Podchaser, RadioPublic, and TuneIn.

Related Videos
A panel of 4 experts on hematologic malignancies
A panel of 6 experts on colorectal cancer
A panel of 6 experts on colorectal cancer
A panel of 4 experts on chronic graft-versus-host disease
A panel of 4 experts on chronic graft-versus-host disease
Jobelle Baldonado, MD
Corey Cutler, MD, MPH, and Hana Safah, MD, experts on GvHD
Corey Cutler, MD, MPH, and Hana Safah, MD, experts on GvHD
Ariel Grajales-Cruz, MD
James K. McCloskey, MD, an expert on leukemia