
|Videos|January 30, 2015
Final Thoughts on Improving Outcomes in CRC
Advertisement
Episodes in this series

In the final segment of the discussion, the expert panel shares their thoughts on the current state of treatment for patients with metastatic colorectal cancer (mCRC).
Dan Haller, MD, explains that overall survival for mCRC has improved 5-fold since he trained as a fellow, back when there was only fluorouracil; in fact, some patients with metastatic disease are now being cured. It’s important to realize how far we’ve come, he comments.
Axel Grothey, MD, says there is no clear winner when it comes to choosing first-line therapy for mCRC. There are several options, and it’s not a one-size-fits-all scenario. The next generation of big questions will be answered by diving into the subset analyses of large phase III studies, he suggests.
Advertisement
Related to this article

Lirafugratinib was added as a category 2A subsequent-line option for cholangiocarcinoma with an FGFR2 fusion or rearrangement and disease progression.

TP53 Comutations, Long-Term Toxicity, and Sunvozertinib Access Shape EGFR+ NSCLC Treatment Decisions
Faculty at an OncLive Scientific Interchange and Workshop discussed factors that help inform treatment selection in advanced EGFR-mutated NSCLC.

Dana-Farber, Mass General Brigham, and Broad Institute researchers uncovered clues to why colorectal cancer can be more aggressive in younger people.

First results from the phase 2 AZUR-1 trial showed sustained clinical complete responses with dostarlimab alone, sparing most patients chemoradiation and surgery.

The FDA approved talazoparib plus enzalutamide in HRR-mutated prostate cancer, ivonescimab improved survival in biliary tract cancer, and more.

Fox Chase researchers identified ANO6 as a potential pancreatic cancer target; blocking it slowed tumor growth and reduced immune suppression in preclinical studies.
Advertisement
Advertisement
Trending on OncLive
1
FDA Approves Amivantamab and Hyaluronidase for Metastatic HNSCC
2
BCG Optimization Becomes a Priority as Durvalumab Gains a Role in High-Risk NMIBC
3
Dr Skoulidis on Divarasib vs Sotorasib or Adagrasib in KRAS G12C–Mutated NSCLC
4
Dr Cai on the Rationale for Evaluating Rocbrutinib Plus R-CHOP in Non-GCB DLBCL and MCL
5














