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Opinion|Videos|April 21, 2026

Future Directions With ADCs in Breast Cancer

Author(s)Neil Iyengar, MD, Kelsey Natsuhara, MD

Neil M. Iyengar, MD, and Kelsey Natsuhara, MD, outline key future directions for antibody-drug conjugate (ADC) development in breast cancer.

Episodes in this series

2 experts are featured in this series.

EP. 1 How Recent ADCs Developments Have Shifted Breast Cancer Care in Clinical Practice

2 experts are featured in this series.

EP. 2 Navigating ADCs and Other Treatment Options in Breast Cancer Care

2 experts are featured in this series.

EP. 3 TROP2-Directed ADCs Are Redefining TNBC Management

2 experts are featured in this series.

EP. 4 How ADCs Affect Sequencing Considerations in TNBC

2 experts are featured in this series.

EP. 5 Exploring ADCs in HR+ Breast Cancer Care

2 experts are featured in this series.

EP. 6 ADCs and Early-Stage HER2+ Breast Cancer Care

2 experts are featured in this series.

EP. 7 Future Directions With ADCs in Breast Cancer

Neil M. Iyengar, MD, and Kelsey Natsuhara, MD, outline key future directions for antibody-drug conjugate (ADC) development in breast cancer. Iyengar discusses ongoing trials evaluating novel ADCs and combination strategies aimed at improving efficacy and overcoming resistance. Natsuhara concludes by emphasizing the need for biomarker-driven approaches and more robust comparative data to optimize ADC integration into clinical practice.

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