Opinion|Videos|April 7, 2026
How ADCs Affect Sequencing Considerations in TNBC
Author(s)Neil Iyengar, MD, Kelsey Natsuhara, MD
Neil M. Iyengar, MD, and Kelsey Natsuhara, MD, discuss how the emergence of antibody-drug conjugates may impact sequencing considerations in triple-negative breast cancer.
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Neil M. Iyengar, MD, and Kelsey Natsuhara, MD, discuss how the integration of antibody-drug conjugates (ADCs) is influencing sequencing strategies in triple-negative breast cancer (TNBC). Iyengar examines the potential for sequential use of ADCs, including those targeting similar antigens such as TROP2. Natsuhara highlights ongoing questions regarding resistance mechanisms and the clinical feasibility of rechallenging patients with ADC therapies.
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