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Treatment with a 100-mg dose of bezuclastinib had a favorable safety and tolerability profile in patients with non-advanced systemic mastocytosis.

100-mg Bezuclastinib Improves Symptoms, Biomarkers in Non-Advanced Systemic Mastocytosis

Mariya Rozenblit, MD, discusses how genomic alterations and TMB influence the efficacy of immune checkpoint inhibitors in HR+ metastatic breast cancer.

Dr Rozenblit on Pembrolizumab Outcomes by TMB Status in HR+ Metastatic Breast Cancer

Maxwell Lloyd, MD, discusses a real-world study of elacestrant outcomes based on prior treatment and ESR1 mutation status in HR+ breast cancer.

Dr Lloyd on the Effects of ESR1 Mutations on Elacestrant Outcomes in HR+ Advanced Breast Cancer

Palbociclib plus anti-HER2 and endocrine therapy improved progression-free survival in hormone receptor–positive, HER2-positive metastatic breast cancer.

Palbociclib Plus Anti-HER2 and Endocrine Therapy Prolongs PFS in HR+/HER2+ Breast Cancer   

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Articles

Caroline Seymour is your initial point of contact for the 

™. She joined the company in 2018 as an assistant editor, with expertise in video production and print/digital publication. Email: cseymour@onclive.com​ 

 as an assistant editor in October 2022. Leveraging an educational background in the life sciences and prior experience conducting interviews in a university setting, she plays a key role in shaping social media strategy, covering live conferences, and producing multimedia content for both print and digital platforms. Email: 

Momelotinib improved OS vs best available therapy in patients with ruxolitinib-experienced myelofibrosis, according to data from a MAIC analysis.

MAIC Points to Improved OS With Momelotinib in Ruxolitinib-Pretreated Myelofibrosis 

Experts across the fields of lung and GI cancer share key information and insights from 2 recent OncLive biomarker consortiums. 

Biomarker-Guided Treatment Approaches Transform Lung and GI Cancer Management

OncLive serves as the connection to oncology, including groundbreaking cancer news and interviews with top oncologists in multimedia formats.

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My Treatment Approach: Graft vs Host Disease

Videos

Nelson J. Chao, MD, MBA, discusses the treatment of acute and chronic graft-versus-host disease through the lens of two patient profiles.

Nelson J. Chao, MD, MBA, presents the patient profile of a 60-year-old man with chronic myeloid leukemia and graft-versus-host disease (GVHD) and shares his initial impressions.

Patient Profile Presentation: A 60-Year-Old Man with Graft-Versus-Host Disease (GVHD)				

Dr Nelson J. Chao reviews how chronic graft-versus-host disease is diagnosed and staged, and the importance of multidisciplinary team communication.

Staging of Chronic GVHD

Nelson J. Chao, MD, MBA, explains the frontline treatment options for chronic GVHD, and when to consider restarting an immunosuppressive regimen.

First-Line Treatment Options for Patients with Chronic GVHD

Dr Nelson J. Chao presents the patient profile of a 67-year-old woman with chronic graft-versus-host disease after a bone marrow donation from a multiparous female.

Patient Profile Presentation: A 67-Year-Old Woman with GVHD

Nelson J. Chao, MD, MBA, details some novel agents being developed for the systemic treatment of GVHD, particularly chronic GVHD.

Investigational Systemic Treatment Options for GVHD

Dr Nelson J. Chao reviews treatment sequencing and speculates on the future of the GVHD treatment landscape.

Treatment Sequencing and Future of GVHD

Pashna Munshi, MD, presents the patient profile of a 44-year-old woman with acute myeloid leukemia diagnosed with grade 2 skin acute GVHD, and shares her initial impressions and what she might have done differently.

Patient Profile Presentation: A 44-Year-Old Woman With Acute Myeloid Leukemia and Graft-Versus-Host Disease (GVHD)

Dr Pashna Munshi describes for what myeloid malignancies allogeneic transplantation is indicated, and its curative potential.

Indications for Allogeneic Stem Cell Transplantation in the Treatment of Myeloid Malignancies

Pashna Munshi, MD, details how age and risk factors into her choice of conditioning regimen for patients with GVHD receiving allogeneic transplant.

Tailored Conditioning Regimens for Patients with GVHD Receiving Allogeneic Transplant

Dr Pashna Munshi explains the currently available options for GVHD prophylaxis and which regimens she utilizes the most in her clinical practice.

Currently Available Options for GVHD Prophylaxis

Pashna Munshi, MD, reviews the differences between acute and chronic GVHD.

Comparing Acute and Chronic GVHD

Pashna Munshi, MD, discusses how acute GVHD is staged and graded, and the common frontline treatment options.

Available Frontline Treatment Options for Patients With Acute GVHD

Closing her discussion, Dr Pashna Munshi reviews recent data on the available treatment options for patients with steroid-refractory acute GVHD.

Current Treatment Options for Patients with Steroid-Refractory Acute GVHD

Insights Video Series

Investigational Systemic Treatment Options for GVHD

EP: 1.Patient Profile Presentation: A 60-Year-Old Man with Graft-Versus-Host Disease (GVHD)

EP: 2.Staging of Chronic GVHD

EP: 3.First-Line Treatment Options for Patients with Chronic GVHD

EP: 4.Patient Profile Presentation: A 67-Year-Old Woman with GVHD

EP: 5.Investigational Systemic Treatment Options for GVHD

EP: 6.Treatment Sequencing and Future of GVHD

EP: 7.Patient Profile Presentation: A 44-Year-Old Woman With Acute Myeloid Leukemia and Graft-Versus-Host Disease (GVHD)

EP: 8.Indications for Allogeneic Stem Cell Transplantation in the Treatment of Myeloid Malignancies

EP: 9.Tailored Conditioning Regimens for Patients with GVHD Receiving Allogeneic Transplant

EP: 10.Currently Available Options for GVHD Prophylaxis

EP: 11.Comparing Acute and Chronic GVHD

EP: 12.Available Frontline Treatment Options for Patients With Acute GVHD

EP: 13.Current Treatment Options for Patients with Steroid-Refractory Acute GVHD

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