Opinion|Videos|March 16, 2026

Sequencing Considerations After the MARIPOSA or FLAURA-2 Regimens in EGFR+ NSCLC

Experts featured in this series.

Samuel Rosner, MD, and Laura Alder, MD, discuss treatment approaches following frontline use of the MARIPOSA or FLAURA-2 regimens in EGFR-mutated NSCLC.

Samuel Rosner, MD, and Laura Alder, MD, explore treatment sequencing considerations following frontline use of combination regimens in EGFR-mutated non–small cell lung cancer. Alder discusses how evolving resistance patterns may influence subsequent therapy selection after combination-based strategies. Rosner highlights current uncertainties in sequencing after these regimens and underscores the need for additional clinical data to guide treatment decisions.


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