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Opinion|Videos|November 28, 2024

Treatment Sequencing in mCRC: Balancing Expert Perspectives and Shared Decision-Making With Patients

Author(s)Marwan G. Fakih, MD, City of Hope, Nilo Azad, MD

Panelists discuss how patient preferences and lifestyle factors are considered when selecting between treatment options for third-line metastatic colorectal cancer (mCRC) and speak about their approaches to shared decision-making and optimal sequencing of therapies based on clinical context and patient needs.

Episodes in this series

EP. 1 Navigating mCRC: Treatment Options in the Third-Line Setting

EP. 1 Navigating mCRC: Treatment Options in the Third-Line Setting

$EP. 2 Nuances With Defining “Refractory” mCRC in the Third-Line Setting$

EP. 2 Nuances With Defining “Refractory” mCRC in the Third-Line Setting

EP. 3 Treatment Sequencing in mCRC: Balancing Expert Perspectives and Shared Decision-Making With Patients

EP. 3 Treatment Sequencing in mCRC: Balancing Expert Perspectives and Shared Decision-Making With Patients

EP. 4 Perspectives on the SUNLIGHT Trial: Study Design and Outcomes

EP. 4 Perspectives on the SUNLIGHT Trial: Study Design and Outcomes

EP. 5 Factoring in Health-Related Quality of Life Outcomes in mCRC Treatment Selection

EP. 5 Factoring in Health-Related Quality of Life Outcomes in mCRC Treatment Selection

EP. 6 Navigating Toxicities: Trifluridine-Tipiracil Plus Bevacizumab

EP. 6 Navigating Toxicities: Trifluridine-Tipiracil Plus Bevacizumab

EP. 7 Dosing Trifluridine-Tipiracil (TAS-102) Plus Bevacizumab Considerations: Hepatic or Renal Impairment

EP. 7 Dosing Trifluridine-Tipiracil (TAS-102) Plus Bevacizumab Considerations: Hepatic or Renal Impairment

EP. 8 Unmet Needs in Third-Line mCRC: Challenges and Opportunities

EP. 8 Unmet Needs in Third-Line mCRC: Challenges and Opportunities

How do you take into account your patient’s preference and/or lifestyle when selecting from these treatment options? What is your approach to shared decision-making?
Is there an optimal sequence in which you give these potential treatment options? Dr Fakih, please also feel free to share your clinical perspective on treatment sequencing.

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