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Balar Addresses Advances in Bladder and Kidney Cancer

Caroline Seymour
Published: Monday, Feb 05, 2018

Arjun V. Balar, MD

Arjun V. Balar, MD
Over the last few years, immunotherapy has taken center stage in the landscape of bladder cancer, with the approval of 5 PD-1/PD-L1 agents: atezolizumab (Tecentriq) and pembrolizumab (Keytruda)—both as first- and second-line therapies—and avelumab (Bavencio), durvalumab (Imfinzi), and nivolumab (Opdivo) in the second-line setting. Next steps in this field, experts have noted, are to study these agents in combination with other novel or existing therapies.

 on Genitourinary (GU) Cancers, Balar, assistant professor, Department of Medicine, director, Genitourinary Medical Oncology Program, NYU Langone’s Perlmutter Cancer Center, and chair of the meeting, discussed the landscape of current and future standards of care for immunotherapy in bladder and kidney cancer.

OncLive: What is the state of immunotherapy in GU cancers?

Balar: At the State of the Science SummitTM on GU Cancers, we spoke about advances in the management of GU cancers and, specifically, my area of focus on the talk was a focus on patients who were treated with metastatic kidney and bladder cancers. In advanced bladder cancer, we have seen a wave of new therapies being approved. These include agents targeting the PD-1 pathway. We have 5 agents approved in the second-line setting, and we have 2 agents approved in the first-line setting. This has been a very active year in terms of drug development. I've covered all of the data that supported the approvals of these agents.
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