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Breast Cancer Stem Cell Research Burgeoning With Vaccines, Epigenetic Therapeutic Developments

Gina Columbus
Published: Thursday, Jun 21, 2018

Max Wicha, MD

Max Wicha, MD

Researchers are in the midst of developing new methods to attack cancer stem cells, specifically in breast cancer, with the use of vaccine and epigenetic therapies, according to Max Wicha, MD.

In an interview, Wicha outlined the evolution of this research and ongoing trials designed to take a deeper dive into targeting these cancer stem cells.

OncLive: What do we know thus far about breast cancer stem cells?

Wicha: It is now becoming very clear that cancers are composed of very heterogeneous cell populations. We know that mutations drive carcinogenesis. However, what has also become clear is that cancers are organized in a fashion in which they have a differentiation pattern that was never found in normal tissues.
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Community Practice Connections™: How Do We Leverage PARP Inhibition Strategies in the Contemporary Treatment of Breast Cancer?May 31, 20191.5
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