Claude Denham, MD
Immunotherapy continues to establish itself in the treatment of patients with non–small cell lung cancer (NSCLC), yet physicians continue to face challenges in later-line settings with resistance, hyperprogression, and optimal responders.
State of the Science Summit™ on Non–Small Cell Lung Cancer, Denham, a medical oncologist at Baylor Charles A. Sammons Cancer Center, discussed the use of immunotherapy beyond the first-line setting in NSCLC. In an interview during the event, he dove deeper into the challenges with immunotherapy in this disease, as well as the promise of combination therapy.
OncLive: Can you give an overview of your presentation?
My topic lays the groundwork for a lot of the others—it is the use of immunotherapy, largely anti–PD-1 therapy, for NSCLC. I reviewed the pivotal trials that have demonstrated that this is essentially the standard of care for most patients in the second-line setting for NSCLC, both adenocarcinoma and squamous cell carcinoma.
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