Amit Singal, MD, UT Southwestern Medical Center

Articles

Future Directions of HCC

April 14th 2021

Stephen L. Chan, MD; Masatoshi Kudo, MD, PhD; and Amit Singal, MD, discuss the future treatment landscape for the management of HCC (hepatocellular carcinoma).

Using AFP as a Biomarker in HCC

April 14th 2021

Stephen L. Chan, MD, comments on the use of AFP as a predictive biomarker in HCC (hepatocellular carcinoma) and the current use of ramucirumab.

Sequencing With Anti-PD-1 Antibodies in HCC

April 14th 2021

Amit Singal, MD; Masatoshi Kudo, MD, PhD; and Stephen L. Chan, MD, share their personal approaches to sequencing with an anti-PD-1 antibody after first-line atezolizumab-bevacizumab in HCC (hepatocellular carcinoma).

Challenges of Sequencing and Biomarkers in Hepatocellular Carcinoma

April 8th 2021

Experts provide insight into the challenges of sequencing and biomarkers when treating advanced HCC.

Role of Single Agent IO in Hepatocellular Carcinoma Frontline Therapies

April 8th 2021

A summary of ongoing clinical data that explore the use of frontline single agent immunotherapy in advanced HCC.

CELESTIAL and RESORCE Trials in HCC

April 7th 2021

Amit Singal, MD, comments on the use of cabozantinib in patients with Child-Pugh A and Child-Pugh B disease as well as regorafenib in advanced stage HCC (hepatocellular carcinoma).

Role of VEGF TKIs for Second-Line Therapy in HCC

April 7th 2021

Considerations for selecting a VEGF TKI (tyrosine kinase inhibitor) in the second-line setting for the management of HCC (hepatocellular carcinoma).

Approaching Second-Line Therapy in HCC

March 31st 2021

Amit Singal, MD, shares his thoughts on approaching second-line therapy for HCC (hepatocellular carcinoma) after first-line atezolizumab-bevacizumab as well as options for patients with Child-Pugh B disease who are ineligible for frontline atezolizumab-bevacizumab.

KEYNOTE-240 and HIMALAYA Trials in Advanced HCC

March 31st 2021

A review of currently available ongoing data for unresectable HCC (hepatocellular carcinoma), including data from the HIMALAYA trial.

Frontline Trials for Unresectable HCC

March 25th 2021

Amit Singal, MD, MS, and Stephen L. Chan, MD, review the IMbrave150, LEAP-002, and CheckMate 9DW trials for unresectable hepatocellular carcinoma.