Gastrointestinal Cancer | Specialty

The OncLive Gastrointestinal Cancer condition center page is a comprehensive resource for clinical news and expert insights on various types of gastrointestinal (GI) cancers, including hepatocellular carcinoma, gastric cancer, pancreatic cancer, colorectal cancer, cholangiocarcinoma, esophageal cancer, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in GI cancers.

ASCO GI Coverage: Australian Study Finds ISH to Be the Best Assessor of HER2 Expression in Gastric Cancer

March 2nd 2011

In situ hybridization (ISH) yields the best results for assessing HER2 expression in gastric cancer, according to a multilaboratory analysis of testing methods.

ASCO GI Coverage: Study Finds Tumor Characteristics Correlate With Survival in Stomach, Esophageal Cancers

March 2nd 2011

An analysis of the National Cancer Institute's Surveillance Epidemiology and End Results (SEER) database showed that advanced gastric or esophageal cancer confers a poor prognosis

ASCO GI Coverage: Imatinib Trough Levels Remain Stable in Most Advanced GIST Patients During Long-Term Treatment

March 2nd 2011

Patients with gastrointestinal stromal tumors (GIST) had stable plasma concentrations of imatinib during long-term treatment, reported Yoon-Koo Kang, MD, PhD, and colleagues at the Gastrointestinal Cancers Symposium.

ASCO GI Coverage: European Study Shows Bevacizumab to Be Ineffective as Adjuvant Therapy

March 2nd 2011

The results of a large, multicenter trial showed that the addition of bevacizumab to adjuvant chemotherapy failed to improve disease-free survival (DFS) compared with chemotherapy alone.

ASCO GI Interview Series: Robert Rosenberg, MD, Discusses Advantages of ColoPrint Test

March 2nd 2011

At the 2011 symposium in San Francisco, California, Oncology & Biotech News spoke with the author of one of the featured presentations at the meeting

ASCO GI Interview Series: Improving Patient Outcomes in Pancreatic Cancer: A Conversation with Mitchell C. Posner, MD

March 2nd 2011

Few cancers have a bleaker outlook than pancreatic cancer.

Oncology Community Facing Severe Drug Shortages

December 19th 2010

Hospitals, pharmacists, and physicians across the United States are reporting shortages of critical anticancer drugs, including carboplatin, cisplatin, dacarbazine, fludarabine, and cytarabine.

Therapeutic Vaccine Improves Survival in Patients with Pancreatic Cancer

August 16th 2010

New pancreatic cancer vaccine findings were presented at the 2007 Gastrointestinal Cancers Symposium, held January 19-21 in Orlando, FL.

FDA Grants Priority Review to Potential Liver Cancer Therapy

June 30th 2010

An oral therapy currently utilized in the treatment of advanced kidney cancer may be on the threshold of obtaining a major new indication.

Sorafenib (Nexavar) Becomes First and Only Approved Treatment of Hepatocellular Carcinoma in Europe

June 29th 2010

The European Commission has granted marketing authorization to sorafenib (Nexavar) for the treatment of patients with hepatocellular carcinoma (HCC), the most common form of liver cancer.

Sorafenib (Nexavar) Is Effective and Well Tolerated in Asian Patients with Advanced Hepatocellular Carcinoma

May 25th 2010

In an oral presentation, Ann-Lii Cheng, MD, PhD, National Taiwan University Hospital, Taipei, Taiwan, highlighted the results of a phase III study evaluating the efficacy and safety of sorafenib in patients from the Asia-Pacific region with advanced hepatocellular carcinoma (HCC).

Treatment with Gemcitabine (Gemzar) for Six Months After Complete Resection of Pancreatic Carcinoma Significantly Increases Disease-free Survival and Overall Survival Compared with Observation Alone

May 25th 2010

Although gemcitabine-based chemotherapy is standard in advanced pancreatic cancer, the role of adjuvant chemotherapy is still incompletely defined.

Colon Cancer Patients Not Getting Recommended Follow-Up Care

May 25th 2010

A new study shows that less than one half of older patients successfully treated for colorectal cancer receive the recommended screening schedule to detect any recurrence of cancer. The analysis indicates poor compliance with recommended monitoring of colorectal cancer survivors could affect survival.

Gastrointestinal Cancers: May 25, 2010

May 25th 2010

The 10th Annual Meeting of the World Congress on Gastrointestinal Cancer was held in Barcelona, Spain, in June. The Congress has grown into a key scientific program that covers malignancies affecting every component of the gastrointestinal tract and all facets of patient care, including screening, diagnosis, and management options for common and uncommon tumors.

Research from the 10th World Congress on Gastrointestinal Cancer: Focus on KRAS

May 24th 2010

This month's issue features highlights from the 10th World Congress on Gastrointestinal Cancer (WCGC), held this past June in Barcelona, Spain. The WCGC is an annual meeting that provides scientific sessions and posters on various malignancies of the gastrointestinal tract.

Colon Cancer Oncogene Identified

May 24th 2010

Scientists at the Dana-Farber Cancer Institute, Boston, Massachusetts, have linked the CDK8 gene to colon cancer, a previously unsuspected association.

Study Links Hepatitis B Exposure to Increased Pancreatic Cancer Risk

May 24th 2010

In what researchers are touting as a first-of-its-kind finding, Houston-based University of Texas M. D. Anderson Cancer Center investigators have discovered a potential connection between exposure to the hepatitis B virus and an increased risk of developing pancreatic cancer.

50th Annual Meeting of the American Society of Hematology

January 27th 2009

Highlights from the 50th Annual Meeting of the American Society of Hematology.

Highlights of 2nd Annual ILCA Conference: Cutting-edge Treatments for Hepatocellular Carcinoma

November 17th 2008

Cutting-edge treatments for hepatocellular carcinoma, including contrast-enhanced ultrasound, combined CRT/TACE, sorafenib, & LCCRT for patients with PVT.

Medical Devices: IOERT for Colorectal Cancer

April 14th 2008

Despite improvements in screening that result in detecting this colorectal cancer in earlier stages, the disease remains the second leading cause of cancer death in men and the third in women.