Novel Agents, T-VEC Combos Mark Next Phase of Oncolytic Immunotherapy Era in Melanoma

Barbara Boughton
Published: Friday, Nov 20, 2015

“Agents such as CVA21 have the potential to induce responses in injected and non-injected lesions and to induce an overall immune response that could affect even metastatic lesions,” Andtbacka noted. “Since they can increase T-cell infiltration into tumors, oncolytic immunotherapies could be used as a rescue strategy to reconstitute the tumor microenvironment in patients resistant to checkpoint inhibitor therapies,” he added.

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