Bringing Bispecific Antibodies to Practice: Operationalizing Care in Lymphoma Across Academic and Community Settings

Experts outline how to start bispecific therapy for relapsed DLBCL, manage CRS/ICANS, and coordinate community–academic lymphoma care.

Learn how clinicians set bispecific immunotherapy expectations, manage early side effects, and decide on outpatient vs inpatient care and monitoring.

Standardize bispecific antibody infusions with nursing training, CRS monitoring, pharmacy checks, and clear academic-community handoffs

Learn how clinicians spot and grade CRS and ICANS early on bispecific antibodies, using home vitals, caregiver alerts, and rapid steroid/toci pathways.

This segment focuses on practical strategies for early recognition and management of CRS in the outpatient setting, along with approaches to prevent infections during bispecific antibody therapy. The panel emphasizes that patient education and clear care pathways are critical for safely managing treatment outside the hospital.

This segment centers on how to maintain continuity of care when patients start bispecific antibodies at an academic center and then transition to community-based treatment, with an emphasis on communication, logistics, and patient engagement.

This final segment highlights practical lessons learned from implementing bispecific antibody therapies and explores how the field may evolve in the coming years. Panelists emphasize that optimizing outcomes requires multidisciplinary collaboration, standardized protocols, and continuous education across clinical teams.