HR+/HER2- Advanced Breast Cancer:

Unmet Needs in 2L Treatment and ET Resistance

Program Objectives:

Review the unmet needs for patients with HR+/HER2- advanced breast cancer with disease progression on or after ET and CDK4/6i

Discuss the role of the PI3K/AKT/PTEN pathway in advanced breast cancer progression and ET resistance

Clinical Perspectives presented by:

Joyce O’Shaughnessy, MD

Celebrating Women Chair in Breast Cancer Research

Baylor University Medical Center

Director, Breast Cancer Research Program

Texas Oncology

US Oncology

Paolo Tarantino, MD

Advanced Research Fellow

Dana-Farber Cancer Institute

Harvard Medical School

This program is sponsored by AstraZeneca and is intended for US healthcare professionals only.