Dr. Aggarwal on the Future of ADT for Patients With Prostate Cancer

Rahul Aggarwal, MD
Published: Wednesday, Nov 01, 2017



Rahul Aggarwal, MD, an assistant professor of Hematology/Oncology, director of the STAND Clinic, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, discusses the future of androgen deprivation therapy (ADT) for patients with prostate cancer.

Studies have shown that early application of these potent therapies demonstrates benefit. There is a lot of ongoing drug development for high-risk patients who do not respond well to ADT or whose prostate-specific antigens do not decline fast enough after induction hormone therapy, says Aggarwal.

The impact of the early use of these therapies on the time to progression remains to be seen. The question also arises of how to treat more aggressive cancer for patients who are castration resistant, had their androgen receptor pathway suppressed, or have already been treated with abiraterone acetate (Zytiga), enzalutamide (Xtandi), or apalutamide.


Rahul Aggarwal, MD, an assistant professor of Hematology/Oncology, director of the STAND Clinic, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, discusses the future of androgen deprivation therapy (ADT) for patients with prostate cancer.

Studies have shown that early application of these potent therapies demonstrates benefit. There is a lot of ongoing drug development for high-risk patients who do not respond well to ADT or whose prostate-specific antigens do not decline fast enough after induction hormone therapy, says Aggarwal.

The impact of the early use of these therapies on the time to progression remains to be seen. The question also arises of how to treat more aggressive cancer for patients who are castration resistant, had their androgen receptor pathway suppressed, or have already been treated with abiraterone acetate (Zytiga), enzalutamide (Xtandi), or apalutamide.



View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: Personalized Sequencing in Castration-Resistant Prostate Cancer: Bridging the Latest Evidence to the Bedside in Clinical ManagementAug 25, 20181.5
Community Practice Connections™: Medical Crossfire®: Translating Lessons Learned with PARP Inhibition to the Treatment of Breast Cancer—Expert Exchanges on Novel Strategies to Personalize CareAug 29, 20181.5
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