Dr. Chandarlapaty on Role of the PI3K Pathway in Breast Cancer

Sarat Chandarlapaty, MD, PhD
Published: Monday, Aug 29, 2016


Sarat Chandarlapaty, MD, PhD, medical oncologist, Memorial Sloan Kettering Cancer Center, discusses the role of the PI3K pathway in patients with metastatic breast cancer.

Although there has not been an agent yet developed that successfully targets PI3K, Chandalapty says the pathway still has a significant role.

PI3K mutations may be less frequent than AKT mutations in patients with metastatic breast cancer, he adds. However, developing a drug that specifically targets PI3K-mutant tumors may help researchers in achieving activity in a difficult-to-treat population.

Sarat Chandarlapaty, MD, PhD, medical oncologist, Memorial Sloan Kettering Cancer Center, discusses the role of the PI3K pathway in patients with metastatic breast cancer.

Although there has not been an agent yet developed that successfully targets PI3K, Chandalapty says the pathway still has a significant role.

PI3K mutations may be less frequent than AKT mutations in patients with metastatic breast cancer, he adds. However, developing a drug that specifically targets PI3K-mutant tumors may help researchers in achieving activity in a difficult-to-treat population.



View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Cancer Summaries and Commentaries™: Update from Chicago: Advances in the Treatment of Breast CancerJul 31, 20181.0
Community Practice Connections™: Medical Crossfire®: Translating Lessons Learned with PARP Inhibition to the Treatment of Breast Cancer—Expert Exchanges on Novel Strategies to Personalize CareAug 29, 20181.5
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