Dr. Chavez on Combination of Ibrutinib Plus Ublituximab in CLL

Julio Chavez, MD
Published: Thursday, Sep 07, 2017



Julio Chavez, MD, of the Department of Malignant Hematology at Moffitt Cancer Center, discusses the potential with the combination of ibrutinib (Imbruvica) and ublituximab (TGR-1101) in patients with chronic lymphocytic leukemia (CLL).

The combination was explored in the GENUINE study, results of which were presented at the 2017 ASCO Annual Meeting. Ublituximab is a monoclonal antibody that is similar to obinutuzumab (Gazyva), Chavez explains. It has shown good activity as a single agent and also in combination with other drugs.

As seen in other clinical trials of combinations with ibrutinib, Chavez says that adding ibrutinib to a monoclonal antibody like ublituximab could lead to better outcomes.
 
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Julio Chavez, MD, of the Department of Malignant Hematology at Moffitt Cancer Center, discusses the potential with the combination of ibrutinib (Imbruvica) and ublituximab (TGR-1101) in patients with chronic lymphocytic leukemia (CLL).

The combination was explored in the GENUINE study, results of which were presented at the 2017 ASCO Annual Meeting. Ublituximab is a monoclonal antibody that is similar to obinutuzumab (Gazyva), Chavez explains. It has shown good activity as a single agent and also in combination with other drugs.

As seen in other clinical trials of combinations with ibrutinib, Chavez says that adding ibrutinib to a monoclonal antibody like ublituximab could lead to better outcomes.
 



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Online CME Activities
TitleExpiration DateCME Credits
Cancer Summaries and Commentaries™: Update from Atlanta: Advances in the Treatment of Chronic Lymphocytic LeukemiaFeb 28, 20190.5
Community Practice Connections™: 2nd Annual International Congress on Immunotherapies in Cancer™: Focus on Practice-Changing ApplicationFeb 28, 20192.0
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