Dr. Dorff on Role of Chemotherapy in mCRPC

Tanya Dorff, MD
Published: Wednesday, Oct 05, 2016



Tanya Dorff, MD, assistant professor of Clinical Medicine, Keck Medicine of University of Southern California, discusses the role of chemotherapy in patients with metastatic castration-resistant prostate cancer (mCRPC) and pivotal clinical trials that have explored this.

Chemotherapy previously was used at the point of castration resistance when hormone therapy was beginning to fail. However, pivotal clinical trials, such as CHAARTED, STAMPEDE, and GETUG 14, demonstrated that early treatment with chemotherapy in newly diagnosed patients with mCRPC who are just beginning hormone therapy will have a more significant benefit.

However, chemotherapy is a toxic treatment, and some high-volume patients may have more of a benefit than others.
 


Tanya Dorff, MD, assistant professor of Clinical Medicine, Keck Medicine of University of Southern California, discusses the role of chemotherapy in patients with metastatic castration-resistant prostate cancer (mCRPC) and pivotal clinical trials that have explored this.

Chemotherapy previously was used at the point of castration resistance when hormone therapy was beginning to fail. However, pivotal clinical trials, such as CHAARTED, STAMPEDE, and GETUG 14, demonstrated that early treatment with chemotherapy in newly diagnosed patients with mCRPC who are just beginning hormone therapy will have a more significant benefit.

However, chemotherapy is a toxic treatment, and some high-volume patients may have more of a benefit than others.
 

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: Personalized Sequencing in Castration-Resistant Prostate Cancer: Bridging the Latest Evidence to the Bedside in Clinical ManagementAug 25, 20181.5
Community Practice Connections™: Precision Medicine for Community Oncologists: Assessing the Role of Tumor-Testing Technologies in Cancer CareNov 30, 20181.0
Publication Bottom Border
Border Publication
x