Dr. Esserman on Personalized Screenings for Breast Cancer

Laura Esserman, MD, MBA
Published: Thursday, Jul 26, 2018



Laura Esserman, MD, MBA, professor, University of California, San Francisco, 2018 Giant of Cancer Care® for Cancer Diagnostics, discusses personalized versus annual screenings for breast cancer. This is the basis behind the WISDOM trial, which is in the process of trying to recruit 100,000 women.

Breast cancer is very heterogeneous, says Esserman. There are many different kinds of the disease, and everyone has different levels of risk to get breast cancer. For these reasons, if patients are receiving personalized therapies, then they should be getting personalized screenings. WISDOM will utilize a comprehensive risk assessment system, looking at the 9 genes that increase risk and over 200 characteristics associated with polygenic risk score, such as breast density, family history, and exposures. All of this, Esserman says, is put into a risk algorithm.

With that, patients are assigned an age to start and stop screening, frequency, and modality. The results will be compared to those of annual screenings.
SELECTED
LANGUAGE


Laura Esserman, MD, MBA, professor, University of California, San Francisco, 2018 Giant of Cancer Care® for Cancer Diagnostics, discusses personalized versus annual screenings for breast cancer. This is the basis behind the WISDOM trial, which is in the process of trying to recruit 100,000 women.

Breast cancer is very heterogeneous, says Esserman. There are many different kinds of the disease, and everyone has different levels of risk to get breast cancer. For these reasons, if patients are receiving personalized therapies, then they should be getting personalized screenings. WISDOM will utilize a comprehensive risk assessment system, looking at the 9 genes that increase risk and over 200 characteristics associated with polygenic risk score, such as breast density, family history, and exposures. All of this, Esserman says, is put into a risk algorithm.

With that, patients are assigned an age to start and stop screening, frequency, and modality. The results will be compared to those of annual screenings.

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: 1st Annual Paris Breast Cancer Conference™Dec 31, 20181.5
35th Annual Chemotherapy Foundation Symposium: Innovative Cancer Therapy for Tomorrow® Clinical Vignette SeriesJan 31, 20192.0
Publication Bottom Border
Border Publication
x