Dr. Frakes on Late Toxicities in HPV-Associated Oropharynx Squamous Cell Carcinoma

Jessica Frakes, MD
Published: Friday, Sep 16, 2016



Jessica Frakes, MD, assistant member, Department of Radiation Oncology, Moffitt Cancer Center, discusses some of the late toxicities seen in patients with HPV-positive oropharynx squamous cell carcinoma.

The most common toxicity reported in the current study was the requirement of a feeding tube. According to Frakes, patients at Moffitt Cancer Center are not prophylactically given feeding tubes, unless they have had significant weight loss pre-treatment.

Six patients had soft tissue necrosis of the skin or jaw, though 4 of those 6 patients had resolution once they received hyperbaric oxygen therapy. Generally speaking, researchers are very aggressive when it comes to managing these late toxicities, says Frakes.
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Jessica Frakes, MD, assistant member, Department of Radiation Oncology, Moffitt Cancer Center, discusses some of the late toxicities seen in patients with HPV-positive oropharynx squamous cell carcinoma.

The most common toxicity reported in the current study was the requirement of a feeding tube. According to Frakes, patients at Moffitt Cancer Center are not prophylactically given feeding tubes, unless they have had significant weight loss pre-treatment.

Six patients had soft tissue necrosis of the skin or jaw, though 4 of those 6 patients had resolution once they received hyperbaric oxygen therapy. Generally speaking, researchers are very aggressive when it comes to managing these late toxicities, says Frakes.

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Online CME Activities
TitleExpiration DateCME Credits
Medical Crossfire®: How Can We Optimize Outcomes in Head and Neck Cancers with Immunotherapeutic Strategies?Oct 31, 20191.5
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