Dr. Higano on Combinations With Radium-223 for Prostate Cancer

Celestia Higano, MD
Published: Friday, Aug 18, 2017



Celestia Higano, MD, professor of medicine and urology at the University of Washington, and a member of the Clinical Research Division at Fred Hutchinson Cancer Research Center, discusses risks associated with combining radium-223 dichloride (Xofigo) for patients with prostate cancer.

Radium-223 has been studied in combination with docetaxel and it has been discovered that there can be significant myelotoxicity, explains Higano. This was unexpected since radium-223 is not associated with this type of adverse event.

It is not recommended to combine these agents but more trials are ongoing to attempt to combine radium-223 with chemotherapy, states Higano.
 


Celestia Higano, MD, professor of medicine and urology at the University of Washington, and a member of the Clinical Research Division at Fred Hutchinson Cancer Research Center, discusses risks associated with combining radium-223 dichloride (Xofigo) for patients with prostate cancer.

Radium-223 has been studied in combination with docetaxel and it has been discovered that there can be significant myelotoxicity, explains Higano. This was unexpected since radium-223 is not associated with this type of adverse event.

It is not recommended to combine these agents but more trials are ongoing to attempt to combine radium-223 with chemotherapy, states Higano.
 

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: Personalized Sequencing in Castration-Resistant Prostate Cancer: Bridging the Latest Evidence to the Bedside in Clinical ManagementAug 25, 20181.5
Community Practice Connections™: Precision Medicine for Community Oncologists: Assessing the Role of Tumor-Testing Technologies in Cancer CareNov 30, 20181.0
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