Dr. Hughes on RT in Elderly Patients With ER+ Breast Cancer

Kevin S. Hughes, MD
Published: Tuesday, Jun 28, 2016


Kevin S. Hughes, MD, co-director, Avon Comprehensive Breast Evaluation Center, medical director, Bermuda Cancer Genetics and Risk Assessment Clinic, Harvard Medical School, Massachusetts General Hospital, discusses treatment with radiation therapy (RT) for elderly patients with ER-positive breast cancer.

In a study, researchers randomized patients aged 70 and older with stage I ER-positive breast cancer to receive RT or no RT. Results showed that there was a decrease in breast cancer recurrence in patients who received RT; however, the decrease was minimal at 7%.

In conclusion, researchers believe that RT is not necessary in elderly patients with early-stage ER-positive breast cancer. This should also be investigated in younger women with luminal A subtypes, where RT may not be needed, Hughes adds.

Kevin S. Hughes, MD, co-director, Avon Comprehensive Breast Evaluation Center, medical director, Bermuda Cancer Genetics and Risk Assessment Clinic, Harvard Medical School, Massachusetts General Hospital, discusses treatment with radiation therapy (RT) for elderly patients with ER-positive breast cancer.

In a study, researchers randomized patients aged 70 and older with stage I ER-positive breast cancer to receive RT or no RT. Results showed that there was a decrease in breast cancer recurrence in patients who received RT; however, the decrease was minimal at 7%.

In conclusion, researchers believe that RT is not necessary in elderly patients with early-stage ER-positive breast cancer. This should also be investigated in younger women with luminal A subtypes, where RT may not be needed, Hughes adds.

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Cancer Summaries and Commentaries™: Update from Chicago: Advances in the Treatment of Breast CancerJul 31, 20181.0
Community Practice Connections™: Medical Crossfire®: Translating Lessons Learned with PARP Inhibition to the Treatment of Breast Cancer—Expert Exchanges on Novel Strategies to Personalize CareAug 29, 20181.5
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