Dr. Induru Discusses Other Mutations in Lung Cancer

Raghava R. Induru, MD
Published: Monday, Nov 20, 2017



Raghava R. Induru, MD, medical oncologist, Levine Cancer Institute, discusses other mutations in lung cancer.

EGFR, ALK, and ROS1, are the most well-known molecular subtypes of lung cancer, and have been used to develop effective treatments, but there are other targets that may help guide treatment.

Of these other targets, BRAF mutations and NTRK mutations are most notable, says Induru. The combination of dabrafenib (Tafinlar) and trametinib (Mekinist) is FDA approved for BRAF-mutated tumors, and entrectinib is showing promise in NTRK-mutated tumors.
 
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Raghava R. Induru, MD, medical oncologist, Levine Cancer Institute, discusses other mutations in lung cancer.

EGFR, ALK, and ROS1, are the most well-known molecular subtypes of lung cancer, and have been used to develop effective treatments, but there are other targets that may help guide treatment.

Of these other targets, BRAF mutations and NTRK mutations are most notable, says Induru. The combination of dabrafenib (Tafinlar) and trametinib (Mekinist) is FDA approved for BRAF-mutated tumors, and entrectinib is showing promise in NTRK-mutated tumors.
 

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TitleExpiration DateCME Credits
Medical Crossfire®: How to Use Liquid Biopsies Throughout the Lung Cancer Treatment Continuum OnlineJan 31, 20191.5
35th Annual Chemotherapy Foundation Symposium: Innovative Cancer Therapy for Tomorrow® Clinical Vignette SeriesJan 31, 20192.0
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