Dr. Jackman on Overcoming Resistance to EGFR Inhibitors in Lung Cancer

David M. Jackman, MD
Published: Monday, Mar 27, 2017



David M. Jackman, MD, medical director of Clinical Pathways, Dana-Farber Cancer Institute, assistant professor of Medicine, Harvard Medical School, discusses overcoming resistance to EGFR inhibitors in non–small cell lung cancer (NSCLC).

When patients develop resistance to their first EGFR inhibitors, they often have T790M mutations. This lead to the development of osimertinib (Tagrisso), adds Jackman.

Resistance in NSCLC is very specific, says Jackman, and as resistance becomes better understood, more targeted therapies can be developed.
 


David M. Jackman, MD, medical director of Clinical Pathways, Dana-Farber Cancer Institute, assistant professor of Medicine, Harvard Medical School, discusses overcoming resistance to EGFR inhibitors in non–small cell lung cancer (NSCLC).

When patients develop resistance to their first EGFR inhibitors, they often have T790M mutations. This lead to the development of osimertinib (Tagrisso), adds Jackman.

Resistance in NSCLC is very specific, says Jackman, and as resistance becomes better understood, more targeted therapies can be developed.
 

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: 18th Annual International Lung Cancer Congress®Oct 31, 20181.5
Clinical Interchange™: Translating Research to Inform Changing Paradigms: Assessment of Emerging Immuno-Oncology Strategies and Combinations across Lung, Head and Neck, and Bladder CancersOct 31, 20182.0
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