Dr. Jeffrey Jones on Idelalisib Combinations in CLL

Jeffrey Jones, MD
Published: Wednesday, Jul 22, 2015



Jeffrey Jones, MD, MPH, Assistant Professor of Internal Medicine and section head of the Chronic Lymphocytic Leukemia (CLL) research program at Ohio State University, discusses idelalisib (Zydelig) combinations in CLL.

Although idealisib has been proven effective as a single-agent therapy, sustained remissions that eventually lead to the discontinuation of therapy may require combination therapies, says Jones.

Idealisib has been studied in combination with monoclonal antibodies, chemotherapy, and most recently novel targeted therapies like ofatumumab (Arzerra). Ofatumumab was shown to improve progression-free survival by 8 months in combination with idealisib compared to ofatumumab alone in a phase III randomized, controlled study.
 


Jeffrey Jones, MD, MPH, Assistant Professor of Internal Medicine and section head of the Chronic Lymphocytic Leukemia (CLL) research program at Ohio State University, discusses idelalisib (Zydelig) combinations in CLL.

Although idealisib has been proven effective as a single-agent therapy, sustained remissions that eventually lead to the discontinuation of therapy may require combination therapies, says Jones.

Idealisib has been studied in combination with monoclonal antibodies, chemotherapy, and most recently novel targeted therapies like ofatumumab (Arzerra). Ofatumumab was shown to improve progression-free survival by 8 months in combination with idealisib compared to ofatumumab alone in a phase III randomized, controlled study.
 



View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Cancer Summaries and Commentaries™: Update from Chicago: Advances in the Treatment of Breast CancerJul 31, 20181.0
Community Practice Connections™: The Next Generation in Renal Cell Carcinoma Treatment: An Oncology Nursing Essentials WorkshopJul 31, 20181.5
Publication Bottom Border
Border Publication
x