Dr. Kelly on Phase Ib Study of Reolysin Plus Bortezomib in Multiple Myeloma
Kevin R. Kelly, MD, PhD, associate professor of Medicine, Keck School of Medicine discusses reolysin plus bortezomib (Velcade) in paitents with multiple myeloma.
This is a phase I clinical trial evaluting an oncolytic virus reolysin in combination with bortezomib in patients with relapsed/refractory multiple myeloma.
The goal is to find the maximum tolerated dose of reolysin. Preliminary results regarding immune system activation are promising.
The study is currently ongoing. Next steps include expanding the study to include more patients to confirm safety.